Co-expression and impact of prostate specific membrane antigen and prostate specific antigen in prostatic pathologies

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Co-expression and impact of prostate specific membrane antigen and prostate specific antigen in prostatic pathologies

BACKGROUND The present study was undertaken to relate the co-expression of prostate-associated antigens, PSMA and PSA, with the degree of vascularization in normal and pathologic (hyperplasia and cancer) prostate tissues to elucidate their possible role in tumor progression. METHODS The study was carried out in 6 normal, 44 benign prostatic hyperplastic and 39 cancerous human prostates. Immun...

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Age Specific Reference Levels of Serum Prostate-Specific Antigen, Prostate Volume and Prostate Specific Antigen Density in Healthy Iranian Men

Background: It is relevant to highlight that there is not a precise and perfect report on either 95 percentile value (upper limit of normal range) or on appropriate reference intervals for serum PSA in Iranian population. Objective: To determine age-specific reference ranges for serum prostate-specific antigen (PSA) concentration and PSA density (PSAD) and prostate volumes in a population of he...

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Prostate specific antigen staining intensity in prostatic adenocarcinoma correlates with serum prostate specific antigen , Bandar Abbas, Iran

Introduction: Prostatic adenocarcinoma is one the most common malignances and the second cause of death in males due to cancer. Prostate Specific Antigen (PZSA) serum level is the first marker to screen such patients. We aimed in this study, to assess the intensity of prostatic adenocarcinoma tissue staining with PSA staining method. Methods: In this corss-sectional study, prostatic adenocarcin...

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Expression of Prostate-Specific Membrane Antigen (PSMA) in Brain Glioma and its Correlation with Tumor Grade

Background & Objective Angiogenesis is an essential component of tumor growth. Expression of PSMA on the neo-vasculature of many solid tumors, including glioblastoma multi-form, has been determined. The pattern of expression suggests that PSMA may play a functional role in angiogenesis. Methods: expression of PSMA in dif...

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age specific reference levels of serum prostate-specific antigen, prostate volume and prostate specific antigen density in healthy iranian men

background: it is relevant to highlight that there is not a precise and perfect report on either 95 percentile value (upper limit of normal range) or on appropriate reference intervals for serum psa in iranian population. objective: to determine age-specific reference ranges for serum prostate-specific antigen (psa) concentration and psa density (psad) and prostate volumes in a population of he...

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ژورنال

عنوان ژورنال: Journal of Experimental & Clinical Cancer Research

سال: 2010

ISSN: 1756-9966

DOI: 10.1186/1756-9966-29-171